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Symbol Name ID |
Hmgb1
high mobility group box 1 MGI:96113 |
| Darker colors indicate more annotations |
| Mouse Phenotypes | increased macrophage apoptosis |
impaired macrophage phagocytosis |
increased susceptibility to induced pancreatitis |
decreased macrophage cell number |
abnormal macrophage physiology |
increased circulating interleukin-1 beta level |
increased circulating interleukin-18 level |
increased circulating interleukin-6 level |
increased circulating tumor necrosis factor level |
increased interleukin-1 beta secretion |
increased interleukin-18 secretion |
increased susceptibility to endotoxin shock |
increased susceptibility to bacterial infection |
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| Availability | Mouse Genotype | |||||||||||||
| Hmgb1tm1.1Dltg/Hmgb1tm1.1Dltg Tg(Pdx1-cre)6Tuv/0 (conditional) |
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| Hmgb1tm1.1Ttg/Hmgb1tm1.1Ttg Lyz2tm1(cre)Ifo/Lyz2+ (conditional) |
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| Hmgb1tm1.1Ttg/Hmgb1tm1.1Ttg Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ (conditional) |
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| Hmgb1tm1.1Ttg/Hmgb1tm1.1Ttg Tg(Itgax-cre)1-1Reiz/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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